72 research outputs found

    Distillability and positivity of partial transposes in general quantum field systems

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    Criteria for distillability, and the property of having a positive partial transpose, are introduced for states of general bipartite quantum systems. The framework is sufficiently general to include systems with an infinite number of degrees of freedom, including quantum fields. We show that a large number of states in relativistic quantum field theory, including the vacuum state and thermal equilibrium states, are distillable over subsystems separated by arbitrary spacelike distances. These results apply to any quantum field model. It will also be shown that these results can be generalized to quantum fields in curved spacetime, leading to the conclusion that there is a large number of quantum field states which are distillable over subsystems separated by an event horizon.Comment: 25 pages, 2 figures. v2: Typos removed, references and comments added. v3: Expanded introduction and reference list. To appear in Rev. Math. Phy

    Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections

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    Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer. A hallmark of chronic hepatitis B is a dysfunctional HBV-specific T-cell response. We therefore designed an immunotherapy driven by naive healthy T cells specific for the HDV antigen (HDAg) to bypass the need for HBV-specific T cells in order to prime PreS1-specific T cells and PreS1 antibodies blocking HBV entry. Methods. Ten combinations of PreS1 and/or HDAg sequences were evaluated for induction of PreS1 antibodies and HBV- and HDV-specific T cells in vitro and in vivo. Neutralization of HBV by PreS1-specific murine and rabbit antibodies was evaluated in cell culture, and rabbit anti-PreS1 were tested for neutralization of HBV in mice repopulated with human hepatocytes. Results. The best vaccine candidate induced T cells to PreS1 and HDAg, and PreS1 antibodies blocking HBV entry in vitro. Importantly, adoptive transfer of PreS1 antibodies prevented, or modulated, HBV infection after a subsequent challenge in humanized mice. Conclusions. We here describe a novel immunotherapy for chronic HBV/HDV that targets viral entry to complement NAs and coming therapies inhibiting viral maturation

    Effects of different long-term soil management systems on some physical and chemical properties and crop production in soils in Berlin-Dahlem and Dedelow- Zalf Müncheberg (Germany)

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    Soil management systems influence the agricultural system as they have in short- and long term period different effects on soil physical and chemical properties, therefore influencing the efficiency of production as well. A well directed choice of tillage equipments leads to a better soil protection and enables a higher fertility which is an important requirement for sustainable agriculture. The aim of this study is to investigate the effects of different soil management systems on some physical and chemical properties and the crop production of these sandy soils. This study demonstrates the first results obtained from the year 2006, performed on the long-term land use experiment with the effects of three different factors (deep and shallow tillage; 17 and 28 cm, lime application; +Ca and –Ca and Farmyard manure; +FYM and –FYM) in Berlin-Dahlem (Germany), Humboldt University of Berlin and the ZALF experimental station at Dedelow (Germany) in 5 different tillage systems (no-tillage, mulch; 10 cm, cultivator; 15 cm, plough; 15 cm and plough; 25 cm). The soil heterogeneity were determined and evaluated with the computer program “Surfer” depending on the different depths of the sand and loam layers. The penetration resistances of both experimental fields showed that the deep tillage systems caused a higher compacted zone in deeper soil layers. It was found that there are significant differences in the soil aggregate stability and pH values between the shallow and deep tillage systems in Berlin-Dahlem. The pH values were significantly higher in the deep tillage systems. The soil organic matter contents were found higher in the deep tillage systems but there were no significant differences. There were also no significant differences in grain yield between these two tillage systems in Berlin-Dahlem

    Generic Bell correlation between arbitrary local algebras in quantum field theory

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    We prove that for any two commuting von Neumann algebras of infinite type, the open set of Bell correlated states for the two algebras is norm dense. We then apply this result to algebraic quantum field theory -- where all local algebras are of infinite type -- in order to show that for any two spacelike separated regions, there is an open dense set of field states that dictate Bell correlations between the regions. We also show that any vector state cyclic for one of a pair of commuting nonabelian von Neumann algebras is entangled (i.e., nonseparable) across the algebras -- from which it follows that every field state with bounded energy is entangled across any two spacelike separated regions.Comment: Third version; correction in the proof of Proposition

    On the spin-statistics connection in curved spacetimes

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    The connection between spin and statistics is examined in the context of locally covariant quantum field theory. A generalization is proposed in which locally covariant theories are defined as functors from a category of framed spacetimes to a category of *-algebras. This allows for a more operational description of theories with spin, and for the derivation of a more general version of the spin-statistics connection in curved spacetimes than previously available. The proof involves a "rigidity argument" that is also applied in the standard setting of locally covariant quantum field theory to show how properties such as Einstein causality can be transferred from Minkowski spacetime to general curved spacetimes.Comment: 17pp. Contribution to the proceedings of the conference "Quantum Mathematical Physics" (Regensburg, October 2014

    Superselection Sectors and General Covariance.I

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    This paper is devoted to the analysis of charged superselection sectors in the framework of the locally covariant quantum field theories. We shall analize sharply localizable charges, and use net-cohomology of J.E. Roberts as a main tool. We show that to any 4-dimensional globally hyperbolic spacetime it is attached a unique, up to equivalence, symmetric tensor \Crm^*-category with conjugates (in case of finite statistics); to any embedding between different spacetimes, the corresponding categories can be embedded, contravariantly, in such a way that all the charged quantum numbers of sectors are preserved. This entails that to any spacetime is associated a unique gauge group, up to isomorphisms, and that to any embedding between two spacetimes there corresponds a group morphism between the related gauge groups. This form of covariance between sectors also brings to light the issue whether local and global sectors are the same. We conjecture this holds that at least on simply connected spacetimes. It is argued that the possible failure might be related to the presence of topological charges. Our analysis seems to describe theories which have a well defined short-distance asymptotic behaviour.Comment: 66 page

    The averaged null energy condition for general quantum field theories in two dimensions

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    It is shown that the averaged null energy condition is fulfilled for a dense, translationally invariant set of vector states in any local quantum field theory in two-dimensional Minkowski spacetime whenever the theory has a mass gap and possesses an energy-momentum tensor. The latter is assumed to be a Wightman field which is local relative to the observables, generates locally the translations, is divergence-free, and energetically bounded. Thus the averaged null energy condition can be deduced from completely generic, standard assumptions for general quantum field theory in two-dimensional flat spacetime.Comment: LateX2e, 16 pages, 1 eps figur

    Topological features of massive bosons on two dimensional Einstein space-time

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    In this paper we tackle the problem of constructing explicit examples of topological cocycles of Roberts' net cohomology, as defined abstractly by Brunetti and Ruzzi. We consider the simple case of massive bosonic quantum field theory on the two dimensional Einstein cylinder. After deriving some crucial results of the algebraic framework of quantization, we address the problem of the construction of the topological cocycles. All constructed cocycles lead to unitarily equivalent representations of the fundamental group of the circle (seen as a diffeomorphic image of all possible Cauchy surfaces). The construction is carried out using only Cauchy data and related net of local algebras on the circle.Comment: 41 pages, title changed, minor changes, typos corrected, references added. Accepted for publication in Ann. Henri Poincare

    Local covariant quantum field theory over spectral geometries

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    A framework which combines ideas from Connes' noncommutative geometry, or spectral geometry, with recent ideas on generally covariant quantum field theory, is proposed in the present work. A certain type of spectral geometries modelling (possibly noncommutative) globally hyperbolic spacetimes is introduced in terms of so-called globally hyperbolic spectral triples. The concept is further generalized to a category of globally hyperbolic spectral geometries whose morphisms describe the generalization of isometric embeddings. Then a local generally covariant quantum field theory is introduced as a covariant functor between such a category of globally hyperbolic spectral geometries and the category of involutive algebras (or *-algebras). Thus, a local covariant quantum field theory over spectral geometries assigns quantum fields not just to a single noncommutative geometry (or noncommutative spacetime), but simultaneously to ``all'' spectral geometries, while respecting the covariance principle demanding that quantum field theories over isomorphic spectral geometries should also be isomorphic. It is suggested that in a quantum theory of gravity a particular class of globally hyperbolic spectral geometries is selected through a dynamical coupling of geometry and matter compatible with the covariance principle.Comment: 21 pages, 2 figure
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